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Home2021Febbraio

[vc_row][vc_column][vc_column_text] La complessa gestione della campagna vaccinale correlata alla pandemia da COVID-19 sta avendo un forte impatto anche sul farmacista ospedaliero che si trova a portare avanti alcune attività, che in realtà sono abituali e insite nella sua professione, ma che, tuttavia, assumono un’evidenza diversa in funzione di alcuni elementi peculiari che stanno caratterizzando questa campagna. Ne abbiamo parlato con Paolo Abrate,

Objective: The purpose of this study was to identify trends in oncology care that allow one to forecast workforce supply and demand, the training and skills needed by the oncology pharmacist for the likely future of oncology care. Methods: Interviews were conducted with experienced oncology pharmacists in leadership roles at 20 organizations balanced by geographic region and type of practice site

Background: In advanced clinical decision support systems, patient characteristics and laboratory values are included in the algorithms that generate alerts. These alerts have a higher specificity than basic medication surveillance alerts. The alerts of advanced clinical decision support systems can be shown directly to the prescriber during order entry, without the risk of generating an overload of irrelevant alerts. We

Since the early days of 2020, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has become a global health concern. Currently, some therapies and vaccines have gotten the FDA approval or emergency use authorization (EUA) for the management of coronavirus disease 2019 (COVID-19). According to the pathophysiology of the disease, several medications have been evaluated in different clinical conditions

SARS-CoV-2 Spike protein is critical for virus infection via engagement of ACE21, and is a major antibody target. Here we report chronic SARS-CoV-2 with reduced sensitivity to neutralising antibodies in an immune suppressed individual treated with convalescent plasma, generating whole genome ultradeep sequences over 23 time points spanning 101 days. Little change was observed in the overall viral population structure

Objectives: The implementation of rapid diagnostic tests (RDTs) may enhance the efficiency of SARS-CoV-2 testing, as RDTs are widely accessible and easy to use. The aim of this study was to evaluate the performance of a diagnosis strategy based on a combination of antigen and IgM/IgG serological RDTs. Methods: Plasma and nasopharyngeal samples were collected between 14 March and 11 April

La produzione di letteratura medico-scientifica è in aumento e l’emergenza sanitaria causata dalla pandemia di CoViD-19 ha determinato un’ulteriore crescita del numero di articoli pubblicati ogni anno sulle riviste internazionali. Orientarsi in questo oceano di informazioni è molto difficile: la valutazione critica della documentazione scientifica richiede tempo e specifiche competenze, non facili da acquisire. Oltre ai medici e agli infermieri, anche

Purpose: Capmatinib, an oral MET kinase inhibitor, has demonstrated its efficacy against non-small cell lung cancer (NSCLC) with MET dysregulation. We investigated its clinical impact in advanced NSCLC with MET exon 14 skipping mutation or gene amplification. Materials and methods: Patients who participated in the screening of a phase II study of capmatinib for advanced NSCLC were enrolled in this study.

Chimeric antigen receptor (CAR) T cell therapy improves the remission rate of refractory/relapsed B-acute lymphoblastic leukemia (R/R B-ALL) patients, but the relapse rate remains high. Recent studies suggest patients who underwent post-chimeric antigen receptor T cell therapy hematopoietic stem cell transplantation (post- HSCT) would achieve durable remission and better survival, but this remains controversial. To this end, we conducted a meta-analysis