Il White Paper costituisce la sintesi di un percorso di condivisione e approfondimento sui temi della governance farmaceutica nato dal confronto con le regioni, l’Istituto Superiore di Sanità, la Commissione Tecnico Scientifica e i rappresentanti dell’industria farmaceutica.
Background: The performance of pharmacists in clinical services contributes to improving outcomes in patient drug therapy. In the context of streamlined resources and high health services' demand, the use of patient selection tools can screen those who would benefit more from a pharmaceutical service. Objective: This review aims to map and describe tools developed for patient selection for pharmaceutical services delivered
Background: The novel coronavirus pneumonia (COVID-19), which was first detected in Wuhan City, has now became a pandemic that affecting patients around the world. Particularly, the community patient population are at high risk of infection and are facing potential failure of proper medication use during the pandemic. Objective: To discuss community pharmacists' role and the content of pharmaceutical care (PC) during
Lymphomas are a diverse group of hematologic malignancies that arise from either T cell, B cell or the natural killer cell lineage. B cell lymphomas arise from gene mutations with critical functions during normal B cell development. Recent advances in the understanding of molecular pathogenesis demonstrate that many different recurrent genomic and molecular abnormalities and dysregulated oncogenic regulatory pathways exist for
Introduction: The purpose of this study was to identify trends in oncology care that allow one to forecast workforce supply and demand, the training and skills needed by the oncology pharmacist for the likely future of oncology care. Methods: Interviews were conducted with experienced oncology pharmacists in leadership roles at 20 organizations balanced by geographic region and type of practice site
Secondo i dati di Farmindustria l'Italia è la prima in Europa per produzione di medicinali con 32 miliardi di euro di fatturato. La maggior parte dei farmaci venduti in Europa però proviene da India e Cina.
Background: As live expectancy and cancer incidence growing, polypharmacy in oncology patients is also increasing, raising the risk of developing potential drug–drug interactions. Objective: To assess the prevalence of clinically relevant potential drug–drug interactions among cancer patients who receive parenteral treatment at our outpatient clinic. Method Retrospective observational study which included randomly selected patients who had received parenteral treatment from november 1st 2016
Importance: Chimeric antigen receptor (CAR) T-cell therapies are currently administered at a limited number of cancer centers and are primarily delivered in an inpatient setting. However, variations in total costs associated with these therapies remain unknown. Objective: To estimate the economic differences in the administration of CAR T-cell therapy by the site of care and the incidence of key adverse events. Design,
Background: Despite the impressive complete remission (CR) induced by CD19 CAR-T cell therapy in B-ALL, the high rate of complete responses is sometimes limited by the emergence of CD19-negative leukemia. Bispecific CAR-modified T cells targeting both CD19 and CD22 may overcome the limitation of CD19-negative relapse. Methods: We here report the design of a bispecific CAR simultaneous targeting of CD19 and
Nella consueta conferenza stampa il Dg dell’Organizzazione mondiale per la sanità ha esortato gli Stati a non avere fretta: “Il coronavirus potrebbe ripresentarsi e l'impatto economico potrebbe essere più grave e prolungato”.
